Reduction of serum free light chains predict renal recovery
نویسندگان
چکیده
منابع مشابه
Quantitation of serum free light chains.
under usual artificial light conditions, and storage of unproc-essed whole blood without antico-agulants at room temperature on the bench. Additionally, we tested the effect of multiple freeze-thaw cycles. 25(OH)–vitamin D 3 measurements were performed on a Cobas E601 an-alyzer (Roche), using the vitamin D 3 (25-OH) assay as recommended by the manufacturer. Samples from each storage experiment ...
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OBJECTIVE Elevated polyclonal serum immunoglobulin free light chains (FLCs; combined FLCκ+FLCλ [cFLC]) are associated with adverse clinical outcomes and increased mortality; we investigated cFLC and cardiovascular disease (CVD) events in type 2 diabetes. RESEARCH DESIGN AND METHODS In a cohort study of 352 south Asian patients with type 2 diabetes, serum cFLC, high-sensitivity C-reactive prot...
متن کاملMeasurement of immunoglobulin free light chains in serum.
but the active/latent isoform proportions were similar (Fig. 1A). Platelet aggregation during clotting (6) may have caused these differences. MMP expression was lower in K 2 E plasma than in LH plasma [14 (3) vs 25 (4) g/L; P Ͻ0.05; Fig. 1A, lane 4 vs lane 5]. The concentrations of MMP-9 forms decreased significantly with increasing amounts of K 2 E during PB collection, whereas MMP-2 was incr...
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Employment or Leadership: None declared. Consultant or Advisory Role: F.C. Wu, Organon International, Bayer Schering Pharma, Eli Lilly, Proctor & Gamble, Pierre Fabre Medicaments, Ferring Pharmaceuticals, TAP Pharmaceuticals, Ardana Bioscience, and GlaxoSmithKline. Stock Ownership: None declared. Honoraria: F.C. Wu, Organon International, Bayer Schering Pharma, Lilly ICOS, Ardana Bioscience, an...
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Multiple myeloma (MM) is a malignancy with excessive production of monoclonal proteins. At disease presentation 30% of MM patients have significant renal impairment which may progress to renal failure requiring dialysis. Besides chemotherapy extracorporeal elimination procedures such as plasma exchange have been applied as adjuvant strategies to eliminate free light chains from circulating bloo...
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ژورنال
عنوان ژورنال: Annals of Hematology
سال: 2009
ISSN: 0939-5555,1432-0584
DOI: 10.1007/s00277-009-0836-1